ABSTRACT
This cross-sectional study estimated a one-time point seroprevalence rate of Chagas disease among people of Latin American descent in Suffolk County, Long Island, New York. Subjects who met the inclusion criteria were screened using the Chagas Detect Plus Rapid Test (InBios, Seattle, WA) with confirmation via Trypanosoma cruzi enzyme immunoassay and T. cruzi immunoblot assay. Administration of a questionnaire regarding demographics and risk factors followed. A seroprevalence rate of 10.74% was found. Identified risk factors included prior residence in a palm leaf house (odds ratio [OR], 10.42; P = 0.003; 95% CI, 2.18-49.76), residence in a house with triatomines (OR, 9.03; P = 0.006; 95% CI, 1.90-42.88), and history of triatomine bite (OR, 9.52; P = 0.009; 95% CI, 1.75-51.77). Our findings emphasize the importance of this frequently underdiagnosed disease and help highlight the importance of early screening among high-risk populations.
Subject(s)
Chagas Disease , Trypanosoma cruzi , Humans , Latin America , New York/epidemiology , Seroepidemiologic Studies , Cross-Sectional Studies , Chagas Disease/epidemiology , Chagas Disease/diagnosisSubject(s)
COVID-19/diagnosis , Coinfection/diagnosis , HIV Infections/diagnosis , Aged , Coinfection/virology , Humans , Male , Middle Aged , New York , Risk FactorsSubject(s)
Brain Neoplasms , Glioblastoma , Granulocytes , Monocytes , Aged , Brain Neoplasms/metabolism , Brain Neoplasms/pathology , Fatal Outcome , Glioblastoma/metabolism , Glioblastoma/pathology , Granulocytes/metabolism , Granulocytes/pathology , Humans , Male , Monocytes/metabolism , Monocytes/pathologySubject(s)
Injections/adverse effects , Mycobacterium Infections, Nontuberculous/diagnosis , Steroids/adverse effects , Tenosynovitis/diagnostic imaging , Tenosynovitis/microbiology , Fingers/microbiology , Fingers/pathology , Humans , Magnetic Resonance Imaging , Male , Mycobacterium Infections, Nontuberculous/drug therapy , Mycobacterium marinum/drug effects , New York , Ships , Steroids/administration & dosage , Tenosynovitis/drug therapy , Water SportsABSTRACT
This review has discussed a link between allergic rhinitis, asthma and systemic lupus erythematosus (SLE) and a case report in this area. A clear link with symptoms of allergic rhinitis, asthma and SLE exists. Several articles found on pubmed in the literature are listed on allergic rhinitis and allergy, Th1-immune responses, mast cells in autoimmunity, total immunoglobulin E levels in lupus, atopic diseases and SLE are reviewed. In addition, risks and correlations, genetic predisposition, environmental factors, immune regulation, elevated serum IgE levels, regulatory B cells for both allergic and autoimmune diseases are mentioned, Asthma and the vascular endothelial cell growth factor, asthma and autoimmune diseases, allergy and autoimmunity, neutrophils, innate and adaptive immunity in the development of SLE, the (Tim) gene family, complement activation in SLE and immunomodulation, hypersensitivity reactions in autoimmunity are discussed.
